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CAR received a daily supplement of 125 g per cow of a rumen-protected L-carnitine product (Carneon 20 Rumin-Pro, Kaesler Nutrition GmbH, Cuxhaven, Germany) with the concentrate feed, resulting in 25 g of L-carnitine per cow and day, while CON received a supplement to equalize the fat content (BergaFat F-100 HP, Berg + Schmidt GmbH & Co

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Flow cytometry analysis for Cas12f-reporter assay The Cas12f-reporter cells and EVs were mixed in the 96-well plates, which were incubated for 3 days at 37 C in a humidified atmosphere of 5% CO 2 (described in Cas12f-reporter assay)

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Do not use following administration of high doses of vitamin D3

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